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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
CYSLTR1
💬
1. CYSLTR1
×
Name
Full Name
CYSLTR1
cysteinyl leukotriene receptor 1
[2]
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
Montelukast
Montelukast
💬
1. CYSLTR1
×
Name
Other Names
Montelukast
Montelukast (INN)
Brondilat (TN)
Montelukast
[8]
6
6
,
13
,
46
,
61
,
63
,
85
,
98
,
228
💬
1. CYSLTR1
×
Disease ID
Name
6
Parkinson disease
13
Multiple sclerosis/Neuromyelitis optica
46
Malignant rheumatoid arthritis
61
Autoimmune hemolytic anemia
63
Idiopathic thrombocytopenic purpura
85
Idiopathic interstitial pneumonia
98
Eosinophilic gastrointestinal disease
228
Bronchiolitis obliterans
2
ADRB2
💬
2. ADRB2
×
Name
Full Name
ADRB2
adrenoceptor beta 2
[9]
Calcium signaling pathway
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
Adrenergic signaling in cardiomyocytes
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Salivary secretion
,
Chemical carcinogenesis - receptor activation
[9]
Calcium signaling pathway
,
cGMP-PKG signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligan
...
Formoterol
Formoterol
💬
2. ADRB2
×
Name
Other Names
Formoterol
Formoterol (INN)
Oxis (TN)
Formoterol
[3]
85
85
,
228
,
299
💬
2. ADRB2
×
Disease ID
Name
85
Idiopathic interstitial pneumonia
228
Bronchiolitis obliterans
299
Cystic fibrosis
3
FGFR1
💬
3. FGFR1
×
Name
Full Name
FGFR1
fibroblast growth factor receptor 1
[16]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
PI3K-Akt signaling pathway
,
Adherens junction
,
Signaling pathways regulating pluripotency of stem cells
,
Thermogenesis
,
Regulation of actin cytoskeleton
,
Parathyroid hormone synthesis, secretion and action
,
Pathways in cancer
,
Proteoglycans in cancer
,
Prostate cancer
,
Melanoma
,
Breast cancer
,
Central carbon metabolism in cancer
[16]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathwa
...
Nintedanib
Nintedanib
💬
3. FGFR1
×
Name
Other Names
Nintedanib
Nintedanib (USAN/INN)
Ofev (TN)
Nintedanib
[5]
51
51
,
85
,
89
,
227
,
228
💬
3. FGFR1
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
89
Lymphangioleiomyomatosis
227
Osler disease
228
Bronchiolitis obliterans
4
FGFR3
💬
4. FGFR3
×
Name
Full Name
FGFR3
fibroblast growth factor receptor 3
[13]
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Signaling pathways regulating pluripotency of stem cells
,
Regulation of actin cytoskeleton
,
Pathways in cancer
,
MicroRNAs in cancer
,
Bladder cancer
,
Central carbon metabolism in cancer
[13]
EGFR tyrosine kinase inhibitor resistance
,
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1
...
Nintedanib
Nintedanib
💬
4. FGFR3
×
Name
Other Names
Nintedanib
Nintedanib (USAN/INN)
Ofev (TN)
Nintedanib
[5]
51
51
,
85
,
89
,
227
,
228
💬
4. FGFR3
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
89
Lymphangioleiomyomatosis
227
Osler disease
228
Bronchiolitis obliterans
5
FGFR2
💬
5. FGFR2
×
Name
Full Name
FGFR2
fibroblast growth factor receptor 2
[13]
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
Endocytosis
,
PI3K-Akt signaling pathway
,
Signaling pathways regulating pluripotency of stem cells
,
Regulation of actin cytoskeleton
,
Pathways in cancer
,
Prostate cancer
,
Gastric cancer
,
Central carbon metabolism in cancer
[13]
EGFR tyrosine kinase inhibitor resistance
,
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1
...
Nintedanib
Nintedanib
💬
5. FGFR2
×
Name
Other Names
Nintedanib
Nintedanib (USAN/INN)
Ofev (TN)
Nintedanib
[5]
51
51
,
85
,
89
,
227
,
228
💬
5. FGFR2
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
89
Lymphangioleiomyomatosis
227
Osler disease
228
Bronchiolitis obliterans
6
FLT1
💬
6. FLT1
×
Name
Full Name
FLT1
fms related receptor tyrosine kinase 1
[9]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
HIF-1 signaling pathway
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Transcriptional misregulation in cancer
,
Rheumatoid arthritis
[9]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
...
Nintedanib
Nintedanib
💬
6. FLT1
×
Name
Other Names
Nintedanib
Nintedanib (USAN/INN)
Ofev (TN)
Nintedanib
[5]
51
51
,
85
,
89
,
227
,
228
💬
6. FLT1
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
89
Lymphangioleiomyomatosis
227
Osler disease
228
Bronchiolitis obliterans
7
FLT4
💬
7. FLT4
×
Name
Full Name
FLT4
fms related receptor tyrosine kinase 4
[8]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
,
PI3K-Akt signaling pathway
,
Focal adhesion
,
Pathways in cancer
,
Breast cancer
[8]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Calcium signaling pathway
...
Nintedanib
Nintedanib
💬
7. FLT4
×
Name
Other Names
Nintedanib
Nintedanib (USAN/INN)
Ofev (TN)
Nintedanib
[5]
51
51
,
85
,
89
,
227
,
228
💬
7. FLT4
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
89
Lymphangioleiomyomatosis
227
Osler disease
228
Bronchiolitis obliterans
8
MTOR
💬
8. MTOR
×
Name
Full Name
MTOR
mechanistic target of rapamycin kinase
[51]
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
HIF-1 signaling pathway
,
Phospholipase D signaling pathway
,
Autophagy - other
,
Autophagy - animal
,
mTOR signaling pathway
,
PI3K-Akt signaling pathway
,
AMPK signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Cellular senescence
,
Apelin signaling pathway
,
Neutrophil extracellular trap formation
,
JAK-STAT signaling pathway
,
Th17 cell differentiation
,
Thermogenesis
,
Insulin signaling pathway
,
Thyroid hormone signaling pathway
,
Adipocytokine signaling pathway
,
Type II diabetes mellitus
,
Insulin resistance
,
Growth hormone synthesis, secretion and action
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Spinocerebellar ataxia
,
Pathways of neurodegeneration - multiple diseases
,
Shigellosis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Human immunodeficiency virus 1 infection
,
Pathways in cancer
,
Proteoglycans in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Colorectal cancer
,
Pancreatic cancer
,
Glioma
,
Prostate cancer
,
Acute myeloid leukemia
,
Breast cancer
,
Hepatocellular carcinoma
,
Gastric cancer
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
[51]
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
ErbB signaling pathway
,
HIF-1
...
Everolimus
Everolimus
💬
8. MTOR
×
Name
Other Names
Everolimus
Everolimus (JAN/USAN/INN)
Afinitor (TN)
Votubia (TN)
Zortress (TN)
Everolimus
[9]
34
34
,
67
,
89
,
96
,
137
,
157
,
158
,
228
,
277
💬
8. MTOR
×
Disease ID
Name
34
Neurofibromatosis
67
Polycystic kidney disease
89
Lymphangioleiomyomatosis
96
Crohn disease
137
Focal cortical dysplasia
157
Sturge-Weber syndrome
158
Tuberous sclerosis
228
Bronchiolitis obliterans
277
Lymphangiomatosis
9
NR3C1
💬
9. NR3C1
×
Name
Full Name
NR3C1
nuclear receptor subfamily 3 group C member 1
[1]
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
Budesonide
Budesonide
💬
9. NR3C1
×
Name
Other Names
Budesonide
Budesonide (JP18/USP/INN)
Entocort EC (TN)
Pulmicort (TN)
Rhinocort (TN)
Uceris (TN)
ORTIKOS
PULMICORT RESPULES
TARPEYO
BUDESONIDE INHALATION
BUDESONIDE INHALATION SUSPENSION
Budesonide
[9]
66
66
,
93
,
94
,
95
,
96
,
97
,
98
,
228
,
299
💬
9. NR3C1
×
Disease ID
Name
66
IgA nephropathy
93
Primary biliary cholangitis
94
Primary sclerosing cholangitis
95
Autoimmune hepatitis
96
Crohn disease
97
Ulcerative colitis
98
Eosinophilic gastrointestinal disease
228
Bronchiolitis obliterans
299
Cystic fibrosis
10
NR3C1
💬
10. NR3C1
×
Name
Full Name
NR3C1
nuclear receptor subfamily 3 group C member 1
[1]
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
Prednisone
Prednisone
💬
10. NR3C1
×
Name
Other Names
Prednisone
Prednisone (USP)
Prednisone monohydrate
Deltasone (TN)
Meticorten (TN)
Rayos (TN)
Prednisone
[45]
2
2
,
11
,
13
,
14
,
19
,
26
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
61
,
63
,
64
,
65
,
66
,
79
,
81
,
84
,
85
,
86
,
95
,
96
,
97
,
113
,
162
,
164
,
205
,
222
,
224
,
228
,
283
,
284
,
288
,
299
,
300
,
307
,
331
💬
[45]
2
,
11
,
13
,
14
,
19
,
26
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
61
,
63
,
64
,
65
,
66
,
79
, ...
10. NR3C1
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
11
Myasthenia gravis
13
Multiple sclerosis/Neuromyelitis optica
14
Chronic inflammatory demyelinating polyneuropathy
19
Lysosomal storage disease
26
HTLV-1-associated myelopathy
35
Pemphigus
40
Takayasu arteritis
41
Giant cell arteritis
42
Polyarteritis nodosa
43
Microscopic polyangiitis
44
Wegener granulomatosis
45
Eosinophilic granulomatosis with Polyangiitis
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
50
Dermatomyositis
51
Scleroderma
53
Sjogren syndrome
61
Autoimmune hemolytic anemia
63
Idiopathic thrombocytopenic purpura
64
Thrombotic thrombocytopenic purpura
65
Primary immunodeficiency
66
IgA nephropathy
79
Homozygous familial hypercholesterolemia
81
Congenital adrenal hyperplasia
84
Sarcoidosis
85
Idiopathic interstitial pneumonia
86
Pulmonary arterial hypertension
95
Autoimmune hepatitis
96
Crohn disease
97
Ulcerative colitis
113
Muscular dystrophy
162
Pemphigoid
164
Oculocutaneous albinism
205
Fragile X syndrome related disease
222
Primary nephrotic syndrome
224
Purpura nephritis
228
Bronchiolitis obliterans
283
Acquired pure red cell aplasia
284
Diamond-Blackfan anemia
288
Autoimmune acquired coagulation factor deficiency
299
Cystic fibrosis
300
IgG4-related disease
307
Canavan disease
331
Idiopathic multicentric castleman disease