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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
CDK4
💬
1. CDK4
×
Name
Full Name
CDK4
cyclin dependent kinase 4
[28]
Endocrine resistance
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Tight junction
,
T cell receptor signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Bladder cancer
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
[28]
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular s
...
Abemaciclib
Abemaciclib
💬
1. CDK4
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
Abemaciclib
[1]
34
34
💬
1. CDK4
×
Disease ID
Name
34
Neurofibromatosis
2
CDK6
💬
2. CDK6
×
Name
Full Name
CDK6
cyclin dependent kinase 6
[23]
Cell cycle
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
MicroRNAs in cancer
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
[23]
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syn
...
Abemaciclib
Abemaciclib
💬
2. CDK6
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
Abemaciclib
[1]
34
34
💬
2. CDK6
×
Disease ID
Name
34
Neurofibromatosis
3
TUBB3
💬
3. TUBB3
×
Name
Full Name
TUBB3
tubulin beta 3 class III
[10]
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
[10]
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Vinblastine
Vinblastine
💬
3. TUBB3
×
Name
Other Names
Vinblastine
Vinblastine (INN)
Vinblastina (TN)
Vinblastine
[2]
34
34
,
65
💬
3. TUBB3
×
Disease ID
Name
34
Neurofibromatosis
65
Primary immunodeficiency
4
TUBB3
💬
4. TUBB3
×
Name
Full Name
TUBB3
tubulin beta 3 class III
[10]
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
[10]
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Vincristine
Vincristine
💬
4. TUBB3
×
Name
Other Names
Vincristine
Vincristine (INN)
Tecnocris (TN)
Vincristine
[4]
26
26
,
34
,
65
,
331
💬
4. TUBB3
×
Disease ID
Name
26
HTLV-1-associated myelopathy
34
Neurofibromatosis
65
Primary immunodeficiency
331
Idiopathic multicentric castleman disease
5
TUBB4A
💬
5. TUBB4A
×
Name
Full Name
TUBB4A
tubulin beta 4A class IVa
[10]
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
[10]
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Vinblastine
Vinblastine
💬
5. TUBB4A
×
Name
Other Names
Vinblastine
Vinblastine (INN)
Vinblastina (TN)
Vinblastine
[2]
34
34
,
65
💬
5. TUBB4A
×
Disease ID
Name
34
Neurofibromatosis
65
Primary immunodeficiency
6
TUBB4A
💬
6. TUBB4A
×
Name
Full Name
TUBB4A
tubulin beta 4A class IVa
[10]
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
[10]
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Vincristine
Vincristine
💬
6. TUBB4A
×
Name
Other Names
Vincristine
Vincristine (INN)
Tecnocris (TN)
Vincristine
[4]
26
26
,
34
,
65
,
331
💬
6. TUBB4A
×
Disease ID
Name
26
HTLV-1-associated myelopathy
34
Neurofibromatosis
65
Primary immunodeficiency
331
Idiopathic multicentric castleman disease
7
TUBB4B
💬
7. TUBB4B
×
Name
Full Name
TUBB4B
tubulin beta 4B class IVb
[10]
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
[10]
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Vinblastine
Vinblastine
💬
7. TUBB4B
×
Name
Other Names
Vinblastine
Vinblastine (INN)
Vinblastina (TN)
Vinblastine
[2]
34
34
,
65
💬
7. TUBB4B
×
Disease ID
Name
34
Neurofibromatosis
65
Primary immunodeficiency
8
TUBB4B
💬
8. TUBB4B
×
Name
Full Name
TUBB4B
tubulin beta 4B class IVb
[10]
Phagosome
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Salmonella infection
[10]
Phagosome
,
Gap junction
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
H
...
Vincristine
Vincristine
💬
8. TUBB4B
×
Name
Other Names
Vincristine
Vincristine (INN)
Tecnocris (TN)
Vincristine
[4]
26
26
,
34
,
65
,
331
💬
8. TUBB4B
×
Disease ID
Name
26
HTLV-1-associated myelopathy
34
Neurofibromatosis
65
Primary immunodeficiency
331
Idiopathic multicentric castleman disease
9
CSF1R
💬
9. CSF1R
×
Name
Full Name
CSF1R
colony stimulating factor 1 receptor
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
PI3K-Akt signaling pathway
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine recept
...
Sunitinib
Sunitinib
💬
9. CSF1R
×
Name
Other Names
Sunitinib
Sunitinib (INN)
Sunitinib
[2]
28
28
,
34
💬
9. CSF1R
×
Disease ID
Name
28
Systemic amyloidosis
34
Neurofibromatosis
10
CSF1R
💬
10. CSF1R
×
Name
Full Name
CSF1R
colony stimulating factor 1 receptor
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
PI3K-Akt signaling pathway
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine recept
...
Pexidartinib
Pexidartinib
💬
10. CSF1R
×
Name
Other Names
Pexidartinib
Pexidartinib (USAN/INN)
Pexidartinib
[1]
34
34
💬
10. CSF1R
×
Disease ID
Name
34
Neurofibromatosis