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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
CDK4
💬
1. CDK4
×
Name
Full Name
CDK4
cyclin dependent kinase 4
[28]
Endocrine resistance
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Tight junction
,
T cell receptor signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Bladder cancer
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
[28]
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular s
...
Abemaciclib
Abemaciclib
💬
1. CDK4
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
Abemaciclib
[1]
34
34
💬
1. CDK4
×
Disease ID
Name
34
Neurofibromatosis
2
CDK6
💬
2. CDK6
×
Name
Full Name
CDK6
cyclin dependent kinase 6
[23]
Cell cycle
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
MicroRNAs in cancer
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
[23]
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syn
...
Abemaciclib
Abemaciclib
💬
2. CDK6
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
Abemaciclib
[1]
34
34
💬
2. CDK6
×
Disease ID
Name
34
Neurofibromatosis
3
CSF1R
💬
3. CSF1R
×
Name
Full Name
CSF1R
colony stimulating factor 1 receptor
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
PI3K-Akt signaling pathway
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine recept
...
Sunitinib
Sunitinib
💬
3. CSF1R
×
Name
Other Names
Sunitinib
Sunitinib (INN)
Sunitinib
[2]
28
28
,
34
💬
3. CSF1R
×
Disease ID
Name
28
Systemic amyloidosis
34
Neurofibromatosis
4
CSF1R
💬
4. CSF1R
×
Name
Full Name
CSF1R
colony stimulating factor 1 receptor
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
PI3K-Akt signaling pathway
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine recept
...
Pexidartinib
Pexidartinib
💬
4. CSF1R
×
Name
Other Names
Pexidartinib
Pexidartinib (USAN/INN)
Pexidartinib
[1]
34
34
💬
4. CSF1R
×
Disease ID
Name
34
Neurofibromatosis
5
CSF2RA
💬
5. CSF2RA
×
Name
Full Name
CSF2RA
colony stimulating factor 2 receptor subunit alpha
[4]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Pathways in cancer
[4]
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
Molgramostim
Molgramostim
💬
5. CSF2RA
×
Name
Other Names
Molgramostim
Molgramostim (USAN/INN)
Molgramostim
[3]
97
97
,
229
,
299
💬
5. CSF2RA
×
Disease ID
Name
97
Ulcerative colitis
229
Autoimmune pulmonary alveolar proteinosis
299
Cystic fibrosis
6
CSF2RA
💬
6. CSF2RA
×
Name
Full Name
CSF2RA
colony stimulating factor 2 receptor subunit alpha
[4]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Pathways in cancer
[4]
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
Regramostim
Regramostim
💬
6. CSF2RA
×
Name
Other Names
Regramostim
Regramostim (USAN/INN)
Regramostim
[1]
229
229
💬
6. CSF2RA
×
Disease ID
Name
229
Autoimmune pulmonary alveolar proteinosis
7
CSF2RA
💬
7. CSF2RA
×
Name
Full Name
CSF2RA
colony stimulating factor 2 receptor subunit alpha
[4]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Pathways in cancer
[4]
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
Sargramostim
Sargramostim
💬
7. CSF2RA
×
Name
Other Names
Sargramostim
Sargramostim (USP/INN)
1438 (genetical recombination) (JAN)
Leukine (TN)
Sargramostim
[7]
6
6
,
28
,
60
,
62
,
96
,
229
,
285
💬
7. CSF2RA
×
Disease ID
Name
6
Parkinson disease
28
Systemic amyloidosis
60
Aplastic anemia
62
Paroxysmal nocturnal hemoglobinuria
96
Crohn disease
229
Autoimmune pulmonary alveolar proteinosis
285
Fanconi anemia
8
CSF2RA
💬
8. CSF2RA
×
Name
Full Name
CSF2RA
colony stimulating factor 2 receptor subunit alpha
[4]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Pathways in cancer
[4]
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
Mavrilimumab
Mavrilimumab
💬
8. CSF2RA
×
Name
Other Names
Mavrilimumab
Mavrilimumab (USAN/INN)
Mavrilimumab
[2]
41
41
,
46
💬
8. CSF2RA
×
Disease ID
Name
41
Giant cell arteritis
46
Malignant rheumatoid arthritis
9
CSF3R
💬
9. CSF3R
×
Name
Full Name
CSF3R
colony stimulating factor 3 receptor
[5]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Pathways in cancer
[5]
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
, ...
Filgrastim
Filgrastim
💬
9. CSF3R
×
Name
Other Names
Filgrastim
Filgrastim (USP/INN)
Filgrastim (genetical recombination) (JP18)
Filgrastim (genetical recombination) [Filgrastim biosimilar 1] (JAN)
Tbo-filgrastim
Filgrastim (genetical recombination) [Filgrastim biosimilar 2] (JAN)
Filgrastim (genetical recombination) [Filgrastim biosimilar 3] (JAN)
Filgrastim-sndz
Filgrastim-aafi
Neupogen (TN)
Nivestym (TN)
Grastofil (TN)
Zarxio (TN)
GRANIX
RELEUKO
Filgrastim
[35]
2
2
,
6
,
11
,
13
,
16
,
22
,
25
,
26
,
28
,
34
,
35
,
36
,
38
,
40
,
41
,
42
,
45
,
46
,
47
,
49
,
51
,
57
,
60
,
62
,
65
,
85
,
96
,
113
,
164
,
256
,
283
,
284
,
285
,
296
,
331
💬
[35]
2
,
6
,
11
,
13
,
16
,
22
,
25
,
26
,
28
,
34
,
35
,
36
,
38
,
40
,
41
,
42
,
45
,
46
,
47
,
49
,
51
,
57
,
60
,
62
,
6
...
9. CSF3R
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
6
Parkinson disease
11
Myasthenia gravis
13
Multiple sclerosis/Neuromyelitis optica
16
Crow-Fukase syndrome
22
Moyamoya disease
25
Progressive multifocal leukoencephalopathy
26
HTLV-1-associated myelopathy
28
Systemic amyloidosis
34
Neurofibromatosis
35
Pemphigus
36
Epidermolysis bullosa
38
Stevens-Johnson syndrome
40
Takayasu arteritis
41
Giant cell arteritis
42
Polyarteritis nodosa
45
Eosinophilic granulomatosis with Polyangiitis
46
Malignant rheumatoid arthritis
47
Buerger disease
49
Systemic lupus erythematosus
51
Scleroderma
57
Idiopathic dilated cardiomyopathy
60
Aplastic anemia
62
Paroxysmal nocturnal hemoglobinuria
65
Primary immunodeficiency
85
Idiopathic interstitial pneumonia
96
Crohn disease
113
Muscular dystrophy
164
Oculocutaneous albinism
256
Muscle glycogenosis
283
Acquired pure red cell aplasia
284
Diamond-Blackfan anemia
285
Fanconi anemia
296
Biliary atresia
331
Idiopathic multicentric castleman disease
10
CSF3R
💬
10. CSF3R
×
Name
Full Name
CSF3R
colony stimulating factor 3 receptor
[5]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Pathways in cancer
[5]
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
, ...
Lenograstim
Lenograstim
💬
10. CSF3R
×
Name
Other Names
Lenograstim
Lenograstim (USAN/INN)
Lenograstim (genetical recombination) (JP18)
Neutrogin (TN)
Lenograstim
[7]
2
2
,
13
,
16
,
18
,
19
,
57
,
65
💬
10. CSF3R
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
13
Multiple sclerosis/Neuromyelitis optica
16
Crow-Fukase syndrome
18
Spinocerebellar degeneration
19
Lysosomal storage disease
57
Idiopathic dilated cardiomyopathy
65
Primary immunodeficiency