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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

SIGMAR1 💬

[2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases

Dextromethorphan 💬

Dextromethorphan

[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
21	Mitochondrial disease
46	Malignant rheumatoid arthritis
78	Hypopituitarism
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
156	Rett syndrome

CD52 💬

Alemtuzumab 💬

Alemtuzumab

[22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
15	Inclusion body myositis
19	Lysosomal storage disease
20	Adrenoleukodystrophy
36	Epidermolysis bullosa
43	Microscopic polyangiitis
44	Wegener granulomatosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
60	Aplastic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
65	Primary immunodeficiency
85	Idiopathic interstitial pneumonia
96	Crohn disease
164	Oculocutaneous albinism
234	Peroxisomal disease (except Adrenoleukodystrophy)
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
326	Osteopetrosis

TNFSF13B 💬

[4] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network ...

Belimumab 💬

Belimumab

[13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
43	Microscopic polyangiitis
44	Wegener granulomatosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
63	Idiopathic thrombocytopenic purpura
66	IgA nephropathy
222	Primary nephrotic syndrome
296	Biliary atresia
300	IgG4-related disease

TNFSF13B 💬

[4] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network ...

Atacicept 💬

Atacicept

[4] 13, 46, 49, 66 💬

CYSLTR1 💬

[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction

Ibudilast 💬

Ibudilast

[2] 2, 13 💬

CYSLTR1 💬

[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction

Montelukast 💬

Montelukast

[8] 6, 13, 46, 61, 63, 85, 98, 228 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
85	Idiopathic interstitial pneumonia
98	Eosinophilic gastrointestinal disease
228	Bronchiolitis obliterans

CA5B 💬

[2] Nitrogen metabolism, Metabolic pathways

Acetazolamide 💬

Acetazolamide

[8] 13, 86, 90, 115, 154, 155, 225, 230 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
86	Pulmonary arterial hypertension
90	Retinitis pigmentosa
115	Hereditary periodic paralysis
154	Epilepsy with continuous spikes and waves during slow sleep
155	Acquired aphasia with convulsive disorder
225	Congenital nephrogenic diabetes insipidus
230	Alveolar hypoventilation syndrome